Leomar Todesco

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BACKGROUND Connective tissue growth factor (CTGF) is a novel, cysteine-rich secreted protein, which is implicated in fibrotic disorders and atherosclerosis. To elucidate the role of CTGF in fibrovascular proliferative retinopathy, we investigated the regulation of CTGF gene expression in a cell line of retinal vascular endothelial cells (RVEC) stimulated(More)
The high-affinity Na+-dependent carnitine transporter OCTN2 (SLC22A5) has a high renal expression and reabsorbs most filtered carnitine. To gain more insight into substrate specificity of OCTN2, we overexpressed hOCTN2 in L6 cells and characterized the structural requirements of substances acting as human OCTN2 (hOCTN2) inhibitors. A 1905-bp fragment(More)
This paper provides an approach to assessing Quality of Context (QoC) parameters in a ubiquitous Ambient Assisted Living (AAL) environment. Initially, the study presents a literature review on QoC, generating taxonomy. Then it introduces the context management architecture used. The proposal is verified with the Siafu simulator in an AAL scenario where the(More)
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