Learn More
The transmitters acetylcholine and gamma-aminobutyrate (GABA) play critical roles in the formation of receptive-field properties of retinal ganglion cells. In rabbit retina, cholinergic amacrine and displaced amacrine cells were identified by immunohistochemical staining for the enzyme choline acetyltransferase and by their avid accumulation of the(More)
1. Receptive field centre sizes of brisk-sustained (X) and brisk-transient (Y) ganglion cells of the cat retina were assessed by three different methods: small spot mapping, area threshold method and spatial resolution. 2. Centre sizes of brisk-sustained (X) cells increased from 20' in the central area to about 70' at an eccentricity of 4.5 mm, centre sizes(More)
We show that the nuclear architecture of rod photoreceptor cells differs fundamentally in nocturnal and diurnal mammals. The rods of diurnal retinas possess the conventional architecture found in nearly all eukaryotic cells, with most heterochromatin situated at the nuclear periphery and euchromatin residing toward the nuclear interior. The rods of(More)
Retinae from species of six orders of mammals (table 1) were processed by an on-the-slide neurofibrillar staining method to establish whether alpha-type ganglion cells are generally present in placental mammals. Alpha cells of the domestic cat, where they were first defined as a type, are used as a standard of reference. Alpha cells were found in all the(More)
Rabbit retinal ganglion cells were retrogradely labeled following injection of rhodamine-labeled microspheres into the medial terminal nucleus. The small fraction of rhodamine-labeled neurons reached their peak concentration within the visual streak and then decreased with increasing eccentricity until none were encountered in the far periphery. The same(More)
Neurofibrillar staining methods were found to stain all alpha cells of the cat retina completely, that is the perikaryon, the axon and the dendritic branches. The dendrites of the alpha cells in vertical sections were found to be unistratified and to occupy two narrow strata in the outer half of the inner plexiform layer. This difference in branching level(More)
Of the 3 anatomically defined classes of ganglion cell in adult cat retina, the alpha and beta cells are the most well documented, thus providing a basis of comparison for developing ganglion cells. Alpha and beta ganglion cells in cat retinae at various ages from birth (P0) to adult were intracellularly injected with Lucifer yellow. At all ages, both cell(More)
Most terrestrial mammals have colour vision based on two spectrally different visual pigments located in two types of retinal cone photoreceptors, i.e. they are cone dichromats with long-to-middle-wave-sensitive (commonly green) L-cones and short-wave-sensitive (commonly blue) S-cones. With visual pigment-specific antibodies, we here demonstrate an absence(More)
In the rabbit retina a distinctive morphological class of large ganglion cells was demonstrated by a combination of intracellular staining with Lucifer Yellow and the quantification of reduced silver-stained preparations. The class is called alpha because of the qualitative and quantitative resemblance to the alpha cells of the cat's retina. Rabbit alpha(More)