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The anatomy of pig skin, neonatal pig skin, and hairless guinea pig skin was investigated with respect to iontophoretic drug transport. Fixed sections of skin were stained with hematoxylin and eosin, and the morphology of the skin appendages was examined. Quantitative measurements of the hair follicle density, diameter and lumen area were obtained, and the(More)
INTRODUCTION . I~'[.ETH O D S . T H E FIRST SERIES OF EXPERI~IENTS . THE SECOND SERIES 01~ EXPERI~'IENTS INVESTIGATION OF FEMALE OFFSPRING ONLY ANALYSIS OF RESULTS ALTER~I~ONS IN OROSSING-OVEI~ DUE TO DIFFERENCES IN VIABILITY ELI~IIN~ITION OF TIIE INFLUENC]~ OF DIFFERENTIAL ~rIABILITY . (1) B y ~he m o ~ h o d of coelficion~s o f a s s o c i a t i o n (2) B(More)
A theoretical model of in vitro iontophoresis that utilizes radial mass transport is presented. The applicability of radial transport to the skin morphology of different species is determined by the density of low-resistance pores, which represents the density of skin appendages such as hair follicles or sweat glands. Radial transport is expected to(More)
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