Leo A Barnes

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Supplementary Figure 1 Integrin αvβ3 is highly e xpressed in a sub-population of hum an pancreatic cancer cells and correlates w ith lym ph node invasion. (a,b) R epresentative im ages of im m unohistochem ical staining for the integrin β3 subunit in hum an pancreatic carcinom a sections from 18 patient sam ples. (a) (top left) β3 is absent or m inim ally(More)
Integrins regulate adhesion-dependent growth, survival and invasion of tumor cells. In particular, expression of integrin αvβ3 is associated with progression of a variety of human tumors. Here, we reveal a novel adhesion-independent role for integrin αvβ3 in pancreatic cancer and other carcinomas. Specifically, αvβ3 expressed in carcinoma cells enhanced(More)
An encapsulated strain of Escherichia coli has been isolated which is hemolytic, pathogenic for mice, and which has served to illustrate further evidence of heterogenetic specificity. The relationship appears to be limited to the serological reactions between the colon organism and Type I antipneumococcic horse serum. Type I antipneumococcic rabbit serum(More)
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