Lenor Kremer

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Analysis of the peptides recognized by CREST sera was carried out in different mouse tissues and cells, including spermatozoa. In all cases, a polypeptide of Mr = 18000 was recognized by the sera and occasionally two other proteins of Mr = 80000 and Mr = 140000 were observed after immunoblotting of nuclear proteins. In both early and late spermatids,(More)
Multiple formins regulate microtubule (MT) arrays, but whether they function individually or in a common pathway is unknown. Lysophosphatidic acid (LPA) stimulates the formation of stabilized detyrosinated MTs (Glu MTs) in NIH3T3 fibroblasts through RhoA and the formin mDia1. Here we show that another formin, INF2, is necessary for mDia1-mediated induction(More)
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