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A novel avian-origin H7N9 influenza strain emerged in China in April 2013. Since its re-emergence in October–November 2013, the number of reported cases has accelerated; more than 220 laboratory-confirmed cases and 112 deaths (case fatality rate of 20–30%) have been reported. The resurgence of H7N9 has re-emphasized the importance of making faster and more… (More)
High strain sequence variability, interference with innate immune mechanisms, and epitope deletion are all examples of strategies that pathogens have evolved to subvert host defenses. To this list we would add another strategy: immune camouflage. Pathogens whose epitope sequences are cross-conserved with multiple human proteins at the TCR-facing residues… (More)
We thank the members of InCoB2014 Scientific Program Committee and the external sub-reviewers (listed alphabetically below) for their valuable time, effort and constructive criticism of manuscripts submitted to InCoB2014 supplement issues of BMC Genomics, BMC Systems Biology or BMC Bioinformatics.