Lennard Herrmann

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In a placebo-controlled double blind study, single oral doses of lofepramine (140 mg and 210 mg) and amitriptyline (100 mg and 150 mg) were given to 5 healthy volunteers. Heart rate, blood pressure, systolic time intervals, and electrical impedance cardiogram were recorded in supine and upright position for 8 hours after drug administration. In addition,(More)