Lenka Chladekova

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UNLABELLED We aimed to study heart rate time irreversibility--a nonlinear qualitative characteristics of heart rate variability indicating complexity of cardiac autonomic control at rest and in response to physiological stress (orthostasis) in never-treated major depressive disorder (MDD) adolescent female patients. METHODS We studied 20 MDD girls and 20(More)
Baroreflex function is usually assessed from spontaneous oscillations of blood pressure (BP) and heart rate (HR) assuming the unidirectional influence from BP to HR. However, the interaction of BP and HR is bidirectional - HR also influences BP. The novel methods based on Granger causality concept for separate analysis of feedback (baroreflex) and(More)
Introduction: Time irreversibility is a characteristic feature of non-equilibrium, complex systems including cardiovascular control mediated by the autonomic nervous system. Its analysis in heart rate variability (HRV) signal represents a new approach to assess cardiovascular regulatory mechanisms. Aim: The purpose of this paper was to assess the changes in(More)
The aim of this study was to investigate the short-term heart rate variability (HRV) as an index of the cardiac autonomic control development in healthy full-term neonates using various new complexity and irreversibility measures. HRV in 20 healthy full-term neonates was compared to HRV recorded in healthy young adults. Besides traditional time and(More)
Background: Obesity is an important risk factor of arterial hypertension. The impairment of baroreflex - a principal blood pressure (BP) control mechanism - could contribute to the development of hypertension in obese patients. Previous studies have found a decreased baroreflex sensitivity (BRS) measured by transfer function analysis of spontaneous BP and(More)
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