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OBJECTIVE Gestational weight gain (GWG) is associated with childhood obesity. We analyzed whether this effect persists into adulthood and is mediated by effects in childhood. DESIGN The design of the study a prospective birth cohort study established in 1959-1961. SUBJECTS The subjects were offspring (n = 4234 of whom 2485 had information from the last(More)
OBJECTIVE To explore whether birth weight (BW) has been increasing in Denmark at the same level as in other countries and whether this increase is paralleled by an increase in birth length (BL) or whether body proportionality, expressed as ponderal index (PI), has changed. RESEARCH METHODS AND PROCEDURES This study used data analysis of information from(More)
It has been suggested that CVD has its origins in early life. An impairment of fetal growth and early postnatal nutrition may have programming effects on cardiovascular physiology. In addition, traditional risk factors for CVD may initiate the atherosclerotic process during childhood. We explored the effect of fat intake, physical activity and lipid profile(More)
BACKGROUND Early nutrition may affect the risk of overweight in later life. OBJECTIVE The objective was to explore the effect of the duration of breastfeeding (BF) and age at introduction of complementary feeding (CF) on body mass index (BMI) during childhood through adulthood. DESIGN The study was based on a subsample of the Copenhagen Perinatal Cohort(More)
OBJECTIVE To assess whether changes in the birth weight distribution or changes in the association of birth weight with the later risk of childhood overweight have contributed to the development of the obesity epidemic. RESEARCH METHODS AND PROCEDURES A Danish population-based cohort study of 124,615 girls and 128,346 boys (ages 6 to 13 years), born(More)
There is an intense interest in the effects of breast-feeding on the offspring and in understanding the mechanisms behind these effects. More than 50 papers are published monthly on topics such as the influence of breast-feeding on aspects of growth, immune-related effects, mental development, and noncommunicable diseases. Most breast-feeding data are(More)
Animal and epidemiologic studies indicate that early nutrition has lasting effects on metabolism and cardiovascular disease risk. In adults, (n-3) long-chain PUFA (LCPUFA) from fish oils improve blood pressure, the lipid profile, and possibly cardiovascular disease mortality. This randomized trial is the first to investigate the effects of fish oil on blood(More)
AIMS To investigate the relation between ponderal index or birth weight and insulin resistance in late childhood. METHODS An observational study of 92-term appropriate-for-gestational age infants was carried out. Weight and length were measured at birth and at 9 months and duration of breast feeding was noted at 9 months. Follow-up examinations at 10(More)
PURPOSE OF REVIEW This review discusses the long-term health effects of breast feeding, based on the most relevant publications from the second half of 2004 and 2005. RECENT FINDINGS The positive effect of breast feeding on later cognitive function continues to be the most consistent and important effect. Also, breast feeding is likely to protect against(More)
BACKGROUND Prenatal life exposures, potentially manifested as altered birth size, may influence the later risk of major chronic diseases through direct biologic effects on disease processes, but also by modifying adult behaviors such as physical activity that may influence later disease risk. METHODS/PRINCIPAL FINDINGS We investigated the association(More)