Lena Lande Wekre

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UNLABELLED Still little is known about the manifestations of osteogenesis imperfecta (OI) in adults. We therefore initiated this study of bone mass, bone turnover and prevalence of fractures in a large cohort of adult patients. We found a surprising low prevalence (10%) of osteoporosis. These patients, however, expressed the most severe disease. PURPOSE(More)
BACKGROUND The aim of this study was to investigate cardiac abnormalities in adults with osteogenesis imperfecta (OI). METHODS The clinical and echocardiographic survey included 99 adults with OI divided into 3 clinical types-I, III, and IV-and 52 controls. Left ventricular end-diastolic dimensions (LVIDds), mass, and 4 aortic diameters were measured by(More)
We examined right ventricular (RV) and ascending pulmonary artery (PA1) dimensions in adults with osteogenesis imperfecta (OI). The survey included 99 adults with OI divided in 3 clinical types (I, III, and IV) and 52 controls. RV and PA1 dimensions were measured by echocardiography and indexed for body surface area. Scoliosis was registered, and spirometry(More)
INTRODUCTION There are no larger studies of adults with osteogenesis imperfecta (OI), focusing on the impact of spinal cord deformities on lung function assessment. OBJECTIVES To assess prevalence and severity of spinal deformities and lung function in an adult population with OI and to explore whether compromise of lung function correlated with(More)
'The Norwegian Polio Study 1994' was performed to make a nation-wide survey of the medical and social situation, and of the needs of anterior poliomyelitis (polio). A questionnaire, consisting of 133 questions with sub-questions, was sent to a total of 2392 polio victims, most of them registered in 'The National Society of Polio Victims' in Norway. 1449(More)
PURPOSES To describe demographical variables, and to study functional ability to perform activities of daily life in adults with osteogenesis imperfecta (OI). METHODS Population-based study. Ninety-seven patients aged 25 years and older, 41 men and 56 women, were included. For the demographical variables, comparison was made to a matched control-group(More)
BACKGROUND Ehlers-Danlos syndrome is the most frequent heritable connective tissue disorder, and a differential diagnosis to known disorders of the muscle and skeletal system. Defects in collagen fibres may lead to hyperelasticity and fragility of connective tissue, which again may result in joint problems, hernia, and rupture of blood vessels and inner(More)
"The Norwegian Polio Study 1994" was conducted in order to survey the medical and social situation and the needs of polio victims. A questionnaire consisting of 133 questions with subquestions was sent to a total of 2,392 polio victims in Norway. 1,449 persons responded, of whom 66% were between 45 and 64 years of age. When specifying new health problems,(More)
BACKGROUND Amyoplasia, the most common form of arthrogryposis is characterized by typical deformities of the joints and replacement of skeletal muscles by fibrous tissue and fat. There is sparse literature on adaptation to adult life with amyoplasia. PURPOSE To describe physical function and activity strategies in adults with amyoplasia, as this knowledge(More)
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