Lena Gunnarsson

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BACKGROUND ANCA-Associated Systemic Vasculitis (AASV) is characterized by leukocytoclasis, accumulation of unscavenged apoptotic and necrotic neutrophils in perivascular tissues. Dysregulation of neutrophil cell death may contribute directly to the pathogenesis of AASV. METHODS Neutrophils from Healthy Blood Donors (HBD), patients with AASV most in(More)
Neutrophils from vasculitis patients exhibit an increased propensity for activation by anti-Abbreviations: ANCA associated vasculitis (AAV), anti-neutrophil cytoplasmic antibody (ANCA), Birmingham vasculitis activity score (BVAS), eosinophilic granulomatosis with polyangiitis (EGPA), granulomatosis with polyangiitis (GPA), healthy control (HC), microscopic(More)
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