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Alzheimer’s disease (AD) is the most common cause of late life dementia. Substantial clinical and experimental evidence supports the hypothesis that amyloid β-protein (Aβ) aggregation produces assemblies with potent neurotoxic properties that cause AD. For this reason, it is important to elucidate the structural dynamics of Aβ aggregation at atomic level.(More)
The hydrogen bond between the Ni atom and the C’j atom is formed if the two atoms are at a distance of 4.0 Å < rij< 4.2 Å and the four pairs of atoms Ni—Cα j, Ni—Nj+1, Cα i+1—C’j, and C’i—C’j are simultaneously at energetically favorable distances (Fig. S1a). These constraints are introduced to correctly model strong angular dependence of the hydrogen bond.(More)
The purpose of our experiment was to determine the abiotic and biotic variables that affect pollinator visitations rates of Rubus canadensis at Waldron Fen in northern Lower Michigan. Five 1m 2 plots were set up, each testing a separate factor and/or acting as a control. These factors included: sunlight/large patch, shade, small patch, petals off, and(More)
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