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The gene encoding the human class II antigen-associated gamma chain is located on chromosome 5.
Cloning and expression of human platelet-derived growth factor alpha and beta receptors.
Platelet-derived growth factor ( PDGF )-induced actin rearrangement is deregulated in cells expressing a mutant Y 778 F PDGF β-receptor
Aino Ruusala 1, Christian Sundberg 2, Ann-Kristin Arvidsson 1,*, Eva Rupp-Thuresson 1,†, Carl-Henrik Heldin 1 and Lena Claesson-Welsh 2,‡ 1The Ludwig Institute for Cancer Research, Biomedical Center,… Expand
[Anti-angiogenic drugs probable complement in cancer therapy].
This review outlines the current status of anti-angiogenic treatment, with emphasis on clinical trials. In pathological growth, vessels become hyperstimulated and dysfunctional, due to overexpression… Expand
Determination of attachment sites for N-linked carbohydrate groups of class II histocompatibility alpha-chain and analysis of possible O-linked glycosylation of alpha- and gamma-chains.
Two glycopeptide fractions were isolated from a tryptic digest of the human class II antigen alpha-subunit, by chromatography on Lens culinaris and Ricinus communis lectin columns, respectively.… Expand
Chapter 18 VEGF Signal Tranduction in Angiogenesis
The development of a number of novel tumor therapies targeting the function of vascular endothelial growth factors (VEGFs) and their receptors has promoted an interest in understanding signal… Expand