Leita Estes

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Ultrastructural morphometric studies were employed to compare the morphology of Leydig cells found in the testes of rats fed ethanol, accounting for 36% of total calories for 6 weeks, and those found in the testes of rats isocalorically fed a diet in which ethanol was isocalorically replaced with dextrimaltose. The testes of alcohol-fed rats weighed(More)
The development of arteriosclerosis is the most serious and common complication in long-term survivors of cardiac transplantation. We have used a variety of inbred rat strains with selected histocompatibility differences to examine the influence of prolonged, mild rejection reactions on the development of pathological changes in long-term cardiac(More)
Four second-generation Illuditi analogues were synthesized and tested for antitumor activity using a metastatic lung carcinoma xenograft model resistant to conventional antitumor agents. One analogue, the parent illudofulvene-derivative called Acylfulvene, inhibited xenograft primary tumor growth and prolonged life span of tumor-bearing animals when(More)
BACKGROUND Antiretroviral therapy for HIV-1 infection has become increasingly complex. The availability of new and potent drugs and progress in understanding the pathogenesis of HIV-1 infection have led to the establishment of new treatment paradigms. The varying dosing regimens, associated toxicities, and the potential for drug-drug and food-drug(More)
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