Leili Yazdchi-Marandi

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BACKGROUND Type 1 diabetes (T1D) is a T-cell mediated autoimmune multifactorial disease. The PTPN22 gene encodes an intracellular lymphoid-specific phosphatase (Lyp) that has been shown to play a negative regulatory role in T cell activation. OBJECTIVES The aim of the present study was to find out associating the PTPN22 C1858T (R620W) polymorphism and T1D(More)
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