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BACKGROUND Our objective was to quantify and predict diabetes risk reduction during the Diabetes Prevention Program Outcomes Study (DPPOS) in participants who returned to normal glucose regulation atContinue Reading
  • Marie-France Hivert, Kathleen A. Jablonski, +10 authors Jose C Florez
  • Medicine
  • Diabetes
  • 2011 (First Publication: 1 April 2011)
  • OBJECTIVE Over 30 loci have been associated with risk of type 2 diabetes at genome-wide statistical significance. Genetic risk scores (GRSs) developed from these loci predict diabetes in the generalContinue Reading
  • Bryan C. Bergman, Leigh Perreault, Devon M. Hunerdosse, Mary C. Koehler, Ali M. Samek, Robert H Eckel
  • Chemistry, Medicine
  • Journal of applied physiology
  • 2010 (First Publication: 1 May 2010)
  • Intramuscular triglyceride (IMTG) has received considerable attention as a potential mechanism promoting insulin resistance. Endurance-trained athletes have high amounts of IMTG but are insulinContinue Reading
  • Leigh Perreault, Kristine Færch
  • Medicine
  • Journal of diabetes and its complications
  • 2014 (First Publication: 1 March 2014)
  • As the global epidemic of type 2 diabetes continues to rise, the time has come to revisit our approach to pre-diabetes. Recently, much ado has been made about screening, diagnosis, pathophysiologyContinue Reading
  • Leigh Perreault, Marinella Temprosa, +8 authors Ronald B. Goldberg
  • Medicine
  • Diabetes care
  • 2014 (First Publication: 1 September 2014)
  • OBJECTIVE Restoration of normal glucose regulation (NGR) in people with prediabetes significantly decreases the risk of future diabetes. We sought to examine whether regression to NGR is alsoContinue Reading