Leigh A. Maher

We don’t have enough information about this author to calculate their statistics. If you think this is an error let us know.
Learn More
The nuclear pregnane X receptor (PXR) plays a central role in regulating xenobiotic metabolism. We now report a novel role for PXR as a critical negative regulator of innate immunity after infection. Pxr(-/-) mice exhibited remarkably elevated pro-inflammatory cytokine and chemokine production following infection with Listeria monocytogenes (Lm). Despite(More)
  • 1