Positive regulatory effects of perioperative probiotic treatment on postoperative liver complications after colorectal liver metastases surgery: a double-center and double-blind randomized clinical…
- Zhihua Liu, Chao Li, Jianping Wang
- MedicineBMC Gastroenterology
- 20 March 2015
Perioperative probiotics treatment could reduce the serum zonulin level, the rate of postoperative septicemia and maintain the liver barrier in patients undergoing CLM surgery and a new model about the regulation of probiotics to liver barrier via clinical regulatory pathway is proposed.
Modified FOLFOX6 With or Without Radiation Versus Fluorouracil and Leucovorin With Radiation in Neoadjuvant Treatment of Locally Advanced Rectal Cancer: Initial Results of the Chinese FOWARC…
- Y. Deng, P. Chi, Jianping Wang
- MedicineJournal of Clinical Oncology
- 27 September 2016
Perioperative mFOLFOX6 alone had inferior results and a lower pCR rate than chemoradiotherapy but led to a similar downstaging rate as fluorouracil-radiotherapy, with less toxicity and fewer postoperative complications.
The effects of perioperative probiotic treatment on serum zonulin concentration and subsequent postoperative infectious complications after colorectal cancer surgery: a double-center and double-blind…
- Zhi‐hua Liu, Mei-jin Huang, Jianping Wang
- MedicineAmerican Journal of Clinical Nutrition
- 2013
Perioperative probiotic treatment can reduce the rate of postoperative septicemia and is associated with reduced serum zonulin concentrations in patients undergoing colectomy and a clinical regulatory model is proposed that might explain this association.
MicroRNA-17-5p promotes chemotherapeutic drug resistance and tumour metastasis of colorectal cancer by repressing PTEN expression
- Lekun Fang, Haoran Li, Burton B. Yang
- Biology, MedicineOncoTarget
- 19 January 2014
It is found that PTEN was a target of miR-17-5p in the colon cancer cells, and their context-specific interactions were responsible for multiple drug-resistance.
Prognostic value of autophagy related proteins ULK1, Beclin 1, ATG3, ATG5, ATG7, ATG9, ATG10, ATG12, LC3B and p62/SQSTM1 in gastric cancer.
- Qing-hua Cao, Fang Liu, Xin-Juan Fan
- Biology, MedicineAmerican journal of translational research
- 2016
The study showed that ATG proteins might serve as novel prognostic biomarkers in gastric cancer, and supply a new valuable insight into cancer treatment targeting autophagy for patients.
PTEN Loss Increases PD-L1 Protein Expression and Affects the Correlation between PD-L1 Expression and Clinical Parameters in Colorectal Cancer
- Minmin Song, De-Feng Chen, Huanliang Liu
- Medicine, BiologyPLoS ONE
- 13 June 2013
PD-L1 can be used to identify CRC patients with high risk of metastasis and poor prognosis and this clinical manifestation may be partly associated with PTEN expression.
Diversity and evolution of conotoxins based on gene expression profiling of Conus litteratus.
- C. Pi, Junlian Liu, A. Xu
- BiologyGenomics
- 1 December 2006
Overexpression of long non-coding RNA-CTD903 inhibits colorectal cancer invasion and migration by repressing Wnt/β-catenin signaling and predicts favorable prognosis.
It is shown that LncRNA-CTD903 acts as a tumor suppressor in CRC and can inhibit cell invasion and migration through repressing Wnt/β-catenin signaling, which plays important roles in EMT and CRC metastasis.
Increased urothelial cancer associated 1 is associated with tumor proliferation and metastasis and predicts poor prognosis in colorectal cancer.
The findings suggested that UCA1 might be an important prognostic indicator in CRC and may be a potential target for diagnosis and gene therapy.
High expression of Beclin-1 predicts favorable prognosis for patients with colorectal cancer.
- Zuli Yang, R. Ghoorun, Jianping Wang
- Medicine, BiologyClinics And Research in Hepatology and…
- 1 February 2015
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