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A fundamental challenge in data center networking is how to efficiently interconnect an exponentially increasing number of servers. This paper presents DCell, a novel network structure that has many desirable features for data center networking. DCell is a recursively defined structure, in which a high-level DCell is constructed from many low-level DCells(More)
Lysine-specific demethylase 1 (LSD1) exerts pathway-specific activity in animal development and has been linked to several high-risk cancers. Here, we report that LSD1 is an integral component of the Mi-2/nucleosome remodeling and deacetylase (NuRD) complex. Transcriptional target analysis revealed that the LSD1/NuRD complexes regulate several cellular(More)
This paper describes our work in integrating three different lexical resources: FrameNet, VerbNet, and WordNet, into a unified, richer knowledge-base, to the end of enabling more robust semantic parsing. The construction of each of these lexical resources has required many years of laborious human effort, and they all have their strengths and shortcomings.(More)
Inference algorithms for topic models are typically designed to be run over an entire collection of documents after they have been observed. However, in many applications of these models, the collection grows over time, making it infeasible to run batch algorithms repeatedly. This problem can be addressed by using online algorithms, which update estimates(More)
The link between Zika virus (ZIKV) infection and microcephaly has raised urgent global alarm. The historical African ZIKV MR766 was recently shown to infect cultured human neural precursor cells (NPCs), but unlike the contemporary ZIKV strains, it is not believed to cause microcephaly. Here we investigated whether the Asian ZIKV strain SZ01 could infect(More)
SOX genes encode a family of high-mobility group transcription factors that play critical roles in organogenesis. The functional specificity of different SOX proteins and the tissue specificity of a particular SOX factor are largely determined by the differential partnership of SOX transcription factors with other transcription regulators, many of which(More)
When conditions are unfavorable, virtually all living cells have the capability of entering a resting state termed quiescence or G0. Many aspects of the quiescence program as well as the mechanisms governing the entry and exit from quiescence remain poorly understood. Previous studies using the budding yeast Saccharomyces cerevisiae have shown that upon(More)
A multiple PCR for the detection of the integrase genes of the three classes of integrons was carried out, and their gene cassettes were characterized in 111 clinical strains of Escherichia coli isolated in Guangzhou City, China during the last 6 years. IntI1 and intI2 genes were detected in 95 isolates (85.6%) and four isolates (3.6%), respectively. No(More)
This paper presents a new web mining scheme for parallel data acquisition. Based on the Document Object Model (DOM), a web page is represented as a DOM tree. Then a DOM tree alignment model is proposed to identify the translationally equivalent texts and hyperlinks between two parallel DOM trees. By tracing the identified parallel hyperlinks, parallel web(More)