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BACKGROUND The use of large doses of opioid analgesics to treat pain after cardiac surgery can prolong the time to tracheal extubation and interfere with recovery of bowel and bladder function in the postoperative period. Therefore, the authors investigated the efficacy of a continuous infusion of bupivacaine 0.25% or 0.5%, at the median sternotomy site,(More)
Lei Chi and Clyde W. Holsapple are in the Decision Science and Information Systems Area, School of Management, Gatton College of Business and Economics, Lexington, KY, USA (Ichi0@uky.edu) (cwhols@uky.edu). Abstract Purpose To develop a process model of interorganizational systems (IOS) collaboration and systematic framework for understanding and classifying(More)
OBJECTIVES Aprotinin is a broad-spectrum serine protease inhibitor that has been shown to attenuate the systemic inflammatory response in patients undergoing cardiac surgery with cardiopulmonary bypass. Although epsilon-aminocaproic acid is similar to aprotinin in its ability to inhibit excessive fibrinolysis (ie, plasmin activity and D-dimer formation),(More)
This study draws on absorptive capacity theory and organizational learning perspective to examine and elaborate the roles of IT in influencing firm innovation in the alliance network context of pharmaceutical industry. We focused on three types of IT-enabled knowledge capabilities and one specific type of alliance network structure structural holes and(More)