Lei Chen

Publications91
h-index23
Citations1,261
Highly Influential Citations9
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Multiplex Immunochips for High-Accuracy Detection of AFP-L3% Based on Surface-Enhanced Raman Scattering: Implications for Early Liver Cancer Diagnosis.
TLDR
A novel concept for the early diagnosis of HCC based on the combination of Raman frequency shift and intensity change, and surface-enhanced Raman scattering (SERS)-based immunochips via AFP-L3 is presented.
Interfacial Charge-Transfer Effects in Semiconductor–Molecule–Metal Structures: Influence of Contact Variation
The charge-transfer resonance of Raman measurements in nanosized semiconductor–molecule–metal interfaces as a function of the excitation energy with four models (Cu–ZnO–PATP–Ag, Cu–Ag–PATP–ZnO,…
Detection of the potential tumor marker of AFP using surface‐enhanced Raman scattering‐based immunoassay
The development of rapid, highly sensitive detection methods for α-fetoprotein (AFP) is very important. As hepatocellular carcinoma is closely related to the level of AFP in the blood, it is…
A highly sensitive microfluidics system for multiplexed surface-enhanced Raman scattering (SERS) detection based on Ag nanodot arrays
We report a method for fabricating a highly sensitive, microfluidic surface-enhanced Raman scattering (SERS) chip with highly ordered Ag nanodot arrays as the enhancement substrate for the detection…
Surface‐enhanced Raman scattering of molecules adsorbed on Co‐doped ZnO nanoparticles
Transition-metal-doped semiconductor nanoparticles (NPs) have been well studied for their optical and catalytic properties but seldom studied by surface-enhanced Raman scattering (SERS). In this…
On-column enrichment and surface-enhanced Raman scattering detection in nanoparticles functionalized porous capillary monolith.
Avidin Induced Silver Aggregation for SERS-based Bioassay
We developed a simple and effective method for the SERS-based detection of protein-small molecule complexes and label-free proteins using avidin-induced silver aggregation. Upon excitation with light…
Highly sensitive determination of iron (III) ion based on phenanthroline probe: Surface-enhanced Raman spectroscopy methods.
Recent Development of SERS Technology: Semiconductor-Based Study
TLDR
An overview of SERS enhancement mechanisms based on semiconductor materials, such as inorganic semiconductors, metal/semiconductor composites, and organic semiconductor are provided.
Magnetic titanium dioxide nanocomposites for surface-enhanced resonance Raman spectroscopic determination and degradation of toxic anilines and phenols.
TLDR
Mesoporous M-TiO2 NCs, functionalized by PATP, can capture toxic anilines and phenols by azo coupling and can be degraded by TiO2-assisted photocatalysis after removal of the loaded hybrid particles from the sample solution with an external magnet.
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