Legesse Zerihun

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This paper analyzes the most extensive database on fluoride distribution in Ethiopia. Of the total 1438 water samples tested, 24.2% had fluoride concentrations above the 1.5 mg/l recommended optimum concentration recommended by WHO. Regionally, by far the highest fluoride levels were recorded in the Rift Valley, where 41.2% of all samples exceeded the 1.5(More)
OBJECTIVE The aim of this study was to assess the daily dietary fluoride intake in children living in two neighbouring villages in the Wonji Shoa Sugar Estate, a rural part of the Ethiopian Rift Valley. METHODS The villages depended on water from different sources: Village A used either river water (Awash River, with 1.8 mg F(-)/L) or ground water (2.1 mg(More)
Numerous plant species are used to treat ailments associated with pyrexia in the indigenous health care delivery system of Ethiopia. Notable among these are Ocimum suave and Ocimum lamiifolium. The objective of the present study was thus to evaluate the antipyretic effects of the aqueous and ethanol extracts of the leaves of Ocimum suave and Ocimum(More)
The practice of traditional medicine for the control of fertility in most parts of Ethiopia is based on the uses of plant medicines for many years. The fact that herbal medicines have been employed for such a long time does not guarantee their efficacy and safety. The aim of the present study was, therefore, to carry out phytochemical screening, efficacy(More)
INTRODUCTION The present study was conducted in Wonji Shoa, a sugar estate in the Ethiopian Rift Valley. Drinking water in the area is provided either by the Awash River or by high-fluoride ground water wells. Defluoridation plants have been installed, but are not in regular use, and fluorosis, dental as well as skeletal, is endemic. The aim of this study(More)
OBJECTIVE To investigate the anti-fertility effect of Ricinus communis seed extract. DESIGN Laboratory-based experiment. SETTING Laboratory of the Department of Pharmacology, Faculty of Medicine, Addis Ababa University, Addis Ababa, Ethiopia in 1996. RESULTS The seed extract was found to possess anti-implantation and abortifacient effects. It was also(More)
BACKGROUND The practice of traditional medicine for the control of fertility in rural Ethiopia is based on folk use of numerous antifertility herbs and Achyranthes aspera is one of these used for this purpose. Many plants are known to possess anti-fertility effect through their action on hypothlamo-pituitary-gonadal axis or direct hormonal effects on(More)
BACKGROUND The practice of traditional medicine for the control of fertility in most parts of Ethiopia is based on the uses of plant medicines for many years. Rumex steudelii Hochst (Polygonaceae), locally known as "Tult" or "Yeberemelas" is one of the traditionally used antifertility plants in Ethiopia. In our previous study, the methanolic extract of R.(More)
BACKGROUND There are quite large number of traditionally used plants that are used to treat ailments associated with fever in the ethnomedical system of Ethiopia. Most of them, however, have not been subjected to scientific investigation for their efficacy and safety. OBJECTIVES To evaluate the antipyretic effects of the aqueous and ethanol extracts of(More)
Myrtus communis has been recommended for relief of insomnia in Ethiopian traditional medicine and aromatherapy. However, no pharmacological studies have yet evaluated its sedative-hypnotic like effect. The aim of this study was to determine if the essential oil of Myrtus communis has sedative-hypnotic like activity. The essential oil of Myrtus communis(More)