• Publications
  • Influence

Claim Your Author Page
Ensure your research is discoverable on Semantic Scholar. Claiming your author page allows you to personalize the information displayed and manage your publications. Semantic Scholar automatically creates author pages based on data aggregated from public sources and our publisher partners.
  • Legesse Adane, Shweta Bhagat, +5 authors Prasad V Bharatam
  • Medicine, Chemistry
  • Bioorganic & medicinal chemistry letters
  • 2014 (First Publication: 15 January 2014)
  • A new class of compounds based on S-benzylated guanylthiourea has been designed as potential PfDHFR inhibitors using computer aided methods (molecular electrostatic potential, molecular docking).Expand
  • Legesse Adane, Dhilon S. Patel, Prasad V Bharatam
  • Chemistry, Medicine
  • Chemical biology & drug design
  • 2010
  • Plasmodium falciparum dihydrofolate reductase (Pf DHFR) enzyme is one of the validated targets in the treatment of malaria using typical antifolates such as cycloguanil and pyrimethamine. However,Expand