Leena Nieminen

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Histone acetylation plays a key role in the regulation of gene expression. The chromatin structure and accessibility of genes to transcription factors is regulated by enzymes that acetylate and deacetylate histones. The Sin3A corepressor complex recruits histone deacetylases and in many cases represses transcription. Here, we report that SAP30L, a close(More)
Branching networks are ubiquitous in nature and their growth often responds to environmental cues dynamically. Using the antibiotic-producing soil bacterium Streptomyces as a model we have developed a flexible mathematical model platform for the study of branched biological networks. Streptomyces form large aggregates in liquid culture that can impair(More)
Description: Volume 41 of Methods in Microbiology is a methods book designed to highlight procedures that will revitalize the purposes and practices of prokaryotic systematics. This volume will notably show that genomics and computational biology are pivotal to the new direction of travel and will emphasise that new developments need to be built upon(More)
Kern WV, et al. Prolonged polyarthralgia in a German traveller with Mayaro virus infection without inflammatory correlates. et al. Direct broad-range detection of al-phaviruses in mosquito extracts. Virol-Genetic relationships among Mayaro and Una viruses suggest distinct patterns of transmission. To the Editor: Toxigenic Coryne-bacterium ulcerans is an(More)
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