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27 Bats are an important reservoir for pathogenic human respiratory and hemorrhagic viruses but 28 only little is known about bat viruses causing gastroenteritis in humans, including rotavirus A 29 strains (RVA). Only three RVA strains have been reported in bats in Kenya (straw-colored 30 fruit bat) and in China (lesser horseshoe and a stoliczka’s trident(More)
A major limitation for better understanding the role of the human gut virome in health and disease is the lack of validated methods that allow high throughput virome analysis. To overcome this, we evaluated the quantitative effect of homogenisation, centrifugation, filtration, chloroform treatment and random amplification on a mock-virome (containing nine(More)
Bats are an important reservoir for zoonotic viruses. To date, only three RVA strains have been reported in bats in Kenya and China. In the current study we investigated the genetic diversity of RVAs in fecal samples from 87 straw-colored fruit bats living in close contact with humans in Cameroon using viral metagenomics. Five (near) complete RVA genomes(More)
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