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  • Sarah J E Wong-Goodrich, Madeline L Pfau, Catherine T Flores, Jennifer A Fraser, Christina L Williams, Lee W Jones
  • 2010
Whole-brain irradiation (WBI) therapy produces progressive learning and memory deficits in patients with primary or secondary brain tumors. Exercise enhances memory and adult hippocampal neurogenesis in the intact brain, so we hypothesized that exercise may be an effective treatment to alleviate consequences of WBI. Previous studies using animal models to(More)
The purpose of this study was to detail the variability found in the exercise intention-behavior relationship and investigate social cognitive and personality correlates of successful intention translation. Participants were 300 undergraduate students who completed measures of exercise social cognition (theory of planned behavior), personality (five-factor(More)
This paper describes how genetic programming was used as an invention machine to automatically synthesize complete designs for six optical lens systems that duplicated the functionality of previously patented lens systems. The automatic synthesis was done "from scratch"-that is, without starting from a pre-existing good design and without pre-specifying the(More)
BACKGROUND We sought to establish whether cardiorespiratory fitness had important implications for long-term cardiovascular risk among individuals classified as low risk by the Framingham Risk Score (10-year coronary heart disease risk <10%). Prognostic factors of long-term cardiovascular risk are needed for low-risk subjects who make up the largest(More)
BACKGROUND The Lung Cancer Exercise Training Study (LUNGEVITY) is a randomized trial to investigate the efficacy of different types of exercise training on cardiorespiratory fitness (VO2peak), patient-reported outcomes, and the organ components that govern VO2peak in post-operative non-small cell lung cancer (NSCLC) patients. METHODS/DESIGN Using a(More)
  • Lee W Jones, Pamela S Douglas, Neil D Eves, P Kelly Marcom, William E Kraus, James E Herndon +3 others
  • 2010
BACKGROUND The Exercise Intensity Trial (EXcITe) is a randomized trial to compare the efficacy of supervised moderate-intensity aerobic training to moderate to high-intensity aerobic training, relative to attention control, on aerobic capacity, physiologic mechanisms, patient-reported outcomes, and biomarkers in women with operable breast cancer following(More)
Recognition of the complex, multidimensional relationship between excess adiposity and cancer control outcomes has motivated the scientific community to seek new research models and paradigms. The National Cancer Institute developed an innovative concept to establish a center grant mechanism in nutrition, energetics, and physical activity, referred to as(More)