Lee W. Henderson

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The objective of the study presented here was to evaluate the relationship of adequacy of dialysis and nutritional status to mortality, technique failure, and morbidity. This was a prospective cohort study of consecutive patients commencing continuous peritoneal dialysis in 14 centers in Canada and the United States. Between September 1 , 1990 and(More)
AIMS This double-blind, randomized, parallel, placebo-controlled investigation evaluated the effects of cross-linked polyelectrolyte (CLP) on serum potassium and measures of congestion in patients with heart failure (HF) and chronic kidney disease (CKD). METHODS AND RESULTS The primary endpoint was change in serum potassium over time. Exploratory(More)
THE PAST It began with the unfortunate formulation of Wolf et al. regarding the rotating drum kidney introduced by Pim Kolff. Wolf ’s calculation of artificial kidney (AK) clearance rate was deliberately modeled after that of Homer Smith for native kidney glomerular filtration rate. Smith measured this important performance value quantitatively so that(More)
CLP is an orally administered, non-absorbed, superabsorbent polymer being developed to increase fecal excretion of sodium, potassium and water in patients with heart failure and end-stage renal disease. This study was conducted to evaluate the safety of CLP, and to explore dose-related effects on fecal weight, fecal and urine sodium and potassium excretion,(More)
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