Lee Edwards

Hendrikus Eggelte1
Stuart Bevan1
Moh Panesar1
1Hendrikus Eggelte
1Stuart Bevan
1Moh Panesar
Learn More
Vanilloid receptor 1 (VR1, TRPV1) is a cation-selective ion channel that is expressed on primary afferent neurons and is upregulated following inflammation and nerve damage. Blockers of this channel may have utility in the treatment of chronic nociceptive and neuropathic pain. Here, we describe the optimization from a high throughput screening hit, of a(More)
  • 1