Learn More
  • Kenneth W. Foreman, Mark Brown, Frances Park, Spencer Emtage, June Harriss, Chhaya Das +5 others
  • 2011
The SET and MYND Domain (SMYD) proteins comprise a unique family of multi-domain SET histone methyltransferases that are implicated in human cancer progression. Here we report an analysis of the crystal structure of the full length human SMYD3 in a complex with an analog of the S-adenosyl methionine (SAM) methyl donor cofactor. The structure revealed an(More)
  • 1