Leandra M. Brettner

  • Citations Per Year
Learn More
A hub protein is one that interacts with many functional partners. The annotation of hub proteins, or more generally the protein-protein interaction “degree” of each gene, requires quality genome-wide data. Data obtained using yeast two-hybrid methods contain many false positive interactions between proteins that rarely encounter each other in living cells,(More)
8 Cooperation through division of labor underpins biological complexity for organisms and communities. In 9 microbes, stochastic differentiation coupled to programmed cell death drives diverse altruistic behaviors that 10 promote cooperation. Utilizing cell death for developmental multicellular programs requires control over 11 differentiation rate to(More)
  • 1