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BACKGROUND Cutaneous allodynia (CA) in migraine is a clinical manifestation of central nervous system sensitization. Several chronic pain syndromes and mood disorders are comorbid with migraine. In this study we examine the relationship of migraine-associated CA with these comorbid conditions. We also evaluate the association of CA with factors such as(More)
OBJECTIVES To examine the prevalence of childhood maltreatment and adult revictimization in migraineurs and the association with sociodemographic factors, depression and anxiety. BACKGROUND Population and practice-based studies have demonstrated an association of childhood abuse and headache in adults, although further details on headache diagnoses,(More)
OBJECTIVE To evaluate in a headache clinic population the relationship of childhood maltreatment on the prevalence of pain conditions comorbid with migraine. BACKGROUND Childhood maltreatment is highly prevalent and has been frequently associated with recurrent headache. The relationship of maltreatment and pain has, however, been a subject of some(More)
OBJECTIVE To examine the headache characteristics of women with migraine and endometriosis (EM), and differences in the prevalence of comorbid conditions between female migraineurs with EM, without EM and nonheadache controls. BACKGROUND Migraine and EM are common conditions in women of reproductive age, and both are influenced by ovarian hormones. The(More)
OBJECTIVES To identify distinct constellations of comorbid disorders occurring in migraineurs, and to examine differences in demographics, headache profiles, and psychosocial features between the comorbidity constellations. METHODS This is a retrospective electronic chart review of consecutive new female outpatients diagnosed with migraine (n = 223) using(More)
BACKGROUND Hemodynamic responses to exercise were assessed in patients with varying degrees of chronic heart failure (CHF) to determine the feasibility of using bioreactance during exercise testing in multicenter studies of CHF. METHODS AND RESULTS A total of 210 symptomatic CHF patients and 22 subjects without heart failure were subjected to(More)
OBJECTIVES To assess in a headache clinic population the relationship of childhood abuse and neglect with migraine characteristics, including type, frequency, disability, allodynia, and age of migraine onset. BACKGROUND Childhood maltreatment is highly prevalent and has been associated with recurrent headache. Maltreatment is associated with many of the(More)
BACKGROUND AND PURPOSE There is mounting evidence of endothelial activation and dysfunction in migraine. Our objectives were to determine in a population of premenopausal women whether endothelial activation markers are associated with migraine. METHODS Women (18 to 50 years) with and without migraine and free from cardiovascular disease were evaluated(More)
OBJECTIVE To discern the effects of depression and anxiety on the migraine-obesity relationship. BACKGROUND Migraine and obesity are highly prevalent conditions and are both independently linked to psychiatric conditions, mainly depression and anxiety. METHODS Data are from an ongoing cross-sectional multicenter study on comorbid conditions in clinic(More)
BACKGROUND With advances in cardiac care, patients with congenital heart disease, including single ventricle (SV) physiology, now survive into adulthood. These patients often suffer from congestive heart failure (CHF) with overexpression of serum biomarkers. Strain and strain rate (SR) may better describe the myocardial mechanics of a failing SV. Our(More)