Leah M. King

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The Bacillus subtilis LexA protein represses the SOS response to DNA damage by binding as a dimer to the consensus operator sequence 5'-CGAACN(4)GTTCG-3'. To characterize the requirements for LexA binding to SOS operators, we determined the operator bases needed for site-specific binding as well as the LexA amino acids required for operator recognition.(More)
Before the introduction of DNA sequencing methods into population genetics by Kreitman (1983), the major source of information about genetic variation among organisms in natural populations came from electrophoretic studies of proteins. The amount of information acquired during 25 years of major electro-phoretic activity is staggering and, for purely(More)
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