Clinical interest in de novo lipogenesis has been sparked by recent studies in rodents demonstrating that de novo lipogenesis specifically in white adipose tissue produces the insulin-sensitizing… (More)
In 2005, the first national psoriasis survey in Germany revealed large deficits in health care particularly in patients with moderate to severe disease. The consecutive goal was to improve health… (More)
Despite the availability of effective therapeutics and evidence-based treatment guidelines, a substantial proportion of patients with moderate-to-severe psoriasis does not receive appropriate care.… (More)
Health-related quality of life (HRQoL) is often markedly impaired in both adults and children with atopic dermatitis. The quality of life of the parents of infants or children with this chronic… (More)
BACKGROUND
In contrast to other European countries, dermatologists in Germany provide health care for a broad spectrum of diseases of the skin and mucous membranes. Current population-based data on… (More)
BACKGROUND
Safety and efficacy of new treatments are analyzed in clinical trials but their capacity to show potential effects of long-term treatment and more than short latency of onset is limited.… (More)
Mesenchymal stromal cells (MSCs) have been shown to display a considerable therapeutic potential in cellular therapies. However, harmful adipogenic maldifferentiation of transplanted MSCs may… (More)
In cell-based assays, FTO overexpression resulted in higher ghrelin mRNA expression and total levels of active ghrelin compared with controls. This finding was paralleled by reduced methylation of… (More)
Telemedicine has become an important element of health care in many countries and profited from the technological progress of the last two decades. Due to the visual character of the dermatological… (More)
Seit 2008 bieten deutsche gesetzliche Krankenversicherungen Hautkrebsscreenings als Standardleistung an. Entsprechend Versicherte ab einem Alter von 35 sind für eine Früherkennungsuntersuchung alle 2… (More)