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High density (HD) SNP genotyping arrays are an important tool for genetic analyses of animals and plants. Although the chicken is one of the most important farm animals, no HD array is yet available for high resolution genetic analysis of this species. We report here the development of a 600 K Affymetrix® Axiom® HD genotyping array designed using SNPs(More)
In this study, we investigated the antibacterial mechanism through the interfacial contacting inhibition behaviors of chitosan antimicrobials against Escherichia coli in solid dispersing state. Chitosan microspheres (CMs) were prepared by emulsification cross-linking reaction, and oleoyl-CMs (OCMs) were obtained by introduction of oleoyl groups to the(More)
Vertebrate skin is characterized by its patterned array of appendages, whether feathers, hairs, or scales. In avian skin the distribution of feathers occurs on two distinct spatial levels. Grouping of feathers within discrete tracts, with bare skin lying between the tracts, is termed the macropattern, while the smaller scale periodic spacing between(More)
Cigarette smoking is a putative environmental risk factor for colon cancer. Nicotine, an active alkaloid in tobacco, has been implicated in carcinogenesis. In the present study, we demonstrated that oral nicotine administration (50 or 200 microg/ml) for 25 days stimulated growth of human colon cancer xenograft in nude mice. It also increased vascularization(More)
Oxalate is widely distributed in the plant kingdom. While excess oxalate in food crops is detrimental to animal and human health, it may play various functional roles in plants, particularly for coping with environmental stresses. Understanding its biosynthetic mechanism in plants, therefore, becomes increasingly important both theoretically and(More)
Unchecked mitogenic signals due to the overexpression of epidermal growth factor (EGF) and its receptor (EGFR) is implicated in the promotion and progression of cancer. In addition, beta-adrenoceptor is involved in the control of cancer cell proliferation. This study sought to elucidate whether a functional connection exists between these two disparate(More)
Location-based social networks (LBSNs) feature friend discovery by location proximity that has attracted hundreds of millions of users world-wide. While leading LBSN providers claim the well-protection of their users' location privacy, for the first time we show through real world attacks that these claims do not hold. In our identified attacks, a malicious(More)
The human cathelicidin LL-37, a pleiotropic host defense peptide, is down-regulated in gastric adenocarcinomas. We therefore investigated whether this peptide suppresses gastric cancer growth. LL-37 lowered gastric cancer cell proliferation and delayed G(1)-S transition in vitro and inhibits the growth of gastric cancer xenograft in vivo. In this(More)
A spatial multi-objective land use optimization model defined by the acronym 'NSGA-II-MOLU' or the 'non-dominated sorting genetic algorithm-II for multi-objective optimization of land use' is proposed for searching for optimal land use scenarios which embrace multiple objectives and constraints extracted from the requirements of users, as well as providing(More)
Remote sensing techniques that provide synoptic and repetitive observations over large geographic areas have become increasingly important in studying the role of agriculture in global carbon cycles. However, it is still challenging to model crop yields based on remotely sensed data due to the variation in radiation use efficiency (RUE) across crop types(More)