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Vertebrate skin is characterized by its patterned array of appendages, whether feathers, hairs, or scales. In avian skin the distribution of feathers occurs on two distinct spatial levels. Grouping of feathers within discrete tracts, with bare skin lying between the tracts, is termed the macropattern, while the smaller scale periodic spacing between(More)
High density (HD) SNP genotyping arrays are an important tool for genetic analyses of animals and plants. Although the chicken is one of the most important farm animals, no HD array is yet available for high resolution genetic analysis of this species. We report here the development of a 600 K Affymetrix® Axiom® HD genotyping array designed using SNPs(More)
Cigarette smoking is a putative environmental risk factor for colon cancer. Nicotine, an active alkaloid in tobacco, has been implicated in carcinogenesis. In the present study, we demonstrated that oral nicotine administration (50 or 200 microg/ml) for 25 days stimulated growth of human colon cancer xenograft in nude mice. It also increased vascularization(More)
A spatial multi-objective land use optimization model defined by the acronym 'NSGA-II-MOLU' or the 'non-dominated sorting genetic algorithm-II for multi-objective optimization of land use' is proposed for searching for optimal land use scenarios which embrace multiple objectives and constraints extracted from the requirements of users, as well as providing(More)
Telecom BI(Business Intelligence) system consists of a set of application programs and technologies for gathering, storing, analyzing and providing access to data, which contribute to manage business information and make decision precisely. However, traditional analysis algorithms meet new challenges as the continued exponential growth in both the volume(More)
Nonverbal behavior is a very important part of human interactions; and how this behavior is tracked and rendered is also key to establishing social presence. Tracking nonverbal behavior is useful not only for rendering signals via avatar, but also for providing clues about interactants. In this paper we describe a novel method of determining identity (i.e.,(More)
Microglia play an important role in neuronal protection and damage. However, the molecular and cellular relationship between microglia and neurons is unclear. We carried out a prospective study to detect that activation of BV2 microglia induced PC12 cell apoptosis in vitro through the TLR4/adapter protein myeloid differentiation factor 88 (MyD88)/nuclear(More)
Seasonally breeding mammals such as sheep use photoperiod, encoded by the nocturnal secretion of the pineal hormone melatonin, as a critical cue to drive hormone rhythms and synchronize reproduction to the most optimal time of year. Melatonin acts directly on the pars tuberalis (PT) of the pituitary, regulating expression of thyrotropin, which then relays(More)
The inference of gene regulatory networks is a key issue for genomic signal processing. This paper addresses the inference of probabilistic Boolean networks (PBNs) from observed temporal sequences of network states. Since a PBN is composed of a finite number of Boolean networks, a basic observation is that the characteristics of a single Boolean network(More)