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OBJECTIVE To describe the establishment and development of the National Tuberculosis Control Programme (NTP) of Vietnam. METHODS Data were obtained from the surveillance system established by the new NTP in 1986 and based on the principles now described as the WHO DOTS strategy. RESULTS The proportion of districts covered by the NTP increased from 40%(More)
OBJECTIVE To determine acquired drug resistance among failure and relapse cases after treatment of new smear-positive tuberculosis. METHODS A cohort of 2901 patients with new smear-positive tuberculosis was enrolled in Vietnam. Sputum samples were stored at enrolment. Upon failure or relapse, another sputum sample was collected. Both were cultured and(More)
SETTING Six provinces in Vietnam where the DOTS strategy was introduced in 1989. OBJECTIVE To assess the impact of improved tuberculosis (TB) control on TB epidemiology in Vietnam. METHODS Data from the surveillance system in the period 1990-2003 were analysed to assess trends of notification rates and the mean ages of notified cases. Data from repeated(More)
Few data address the outcomes of patients who have multidrug-resistant tuberculosis (MDR-TB), defined as resistance to at least isoniazid and rifampin, and who receive a standard World Health Organization (WHO) recommended retreatment regimen after relapse or failure with initial treatment. In this case series, we examined treatment outcomes of a(More)
Among 2,901 new smear-positive tuberculosis cases in Ho Chi Minh City, Vietnam, 40 cases of treatment failure and 39 relapsing cases were diagnosed. All initial and follow-up Mycobacterium tuberculosis isolates of these case-patients had (nearly) identical restriction fragment length polymorphism patterns, and the Beijing genotype was a significant risk(More)
BACKGROUND Vietnam has an emerging human immunodeficiency virus (HIV) epidemic (estimated population prevalence 0.5%), but valid data on HIV prevalence among tuberculosis (TB) patients are limited. Recent increases in TB notification rates among young adults may be related to HIV. OBJECTIVES To assess the prevalence of HIV infection among smear-positive(More)
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