Le Ahn Luong

Learn More
OBJECTIVE Interleukin (IL)-6-mediated inflammation is involved in cardiovascular disease (CVD). We assessed IL-6 levels and the -174G>C genotype in a case-control study of men and women (average age 73 years) within the Cardiovascular Health Study. METHODS AND RESULTS Cases included incident angina, myocardial infarction (MI), and stroke (5-year(More)
The functional 5A/6A polymorphism of the stromelysin-1 promoter has been implicated as a potential genetic marker for the progression of angiographically determined atherosclerosis in patients with coronary artery disease. Recently, a novel interleukin-6 (IL-6) gene functional G/C polymorphism at -174 in the promoter has also been reported. In this study,(More)
Renin-angiotensin systems may mediate cardiovascular disease pathogenesis through a balance of actions of angiotensin II on (potentially proatherogenic) constitutive type 1 (AT1R) and (potentially antiatherogenic) inducible type 2 (AT2R) receptors. We explored such potential roles in a prospective candidate gene association study. Cardiovascular end points(More)
Objective—Interleukin (IL)-6 –mediated inflammation is involved in cardiovascular disease (CVD). We assessed IL-6 levels and the Ϫ174GϾC genotype in a case-control study of men and women (average age 73 years) within the Cardiovascular Health Study. Methods and Results—Cases included incident angina, myocardial infarction (MI), and stroke (5-year(More)
  • 1