Layzon Antonio Lemos da Silva

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INTRODUCTION Triterpenes are one of the largest secondary metabolites groups spread in the plant kingdom with various skeletons. These metabolites have showed various bioactivities including anti-inflammatory activity. OBJECTIVE The study aims to explore the mass spectrometry fragmentation of donellanic acids A-C (DA A-C), three compounds identified from(More)
BACKGROUND The chemical characterization is essential to validate the pharmaceutical use of vegetable raw materials. Ultraviolet spectroscopy is an important technique to determine flavonoids, which are important active compounds from Ocimum basilicum. OBJECTIVE The objective of this work was to optimize a spectrophotometric method, based on(More)
CONTEXT Jatropha isabellei Müll. Arg. (Euphorbiaceae) has been used in the traditional medicine to treat arthritis. OBJECTIVE To evaluate the anti-inflammatory and antinociceptive activities of the dichloromethane fraction (DFJi) from underground parts of J. isabellei, and to develop an analytical method to quantify the diterpene jatrophone. MATERIALS(More)
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