Lawrence Yao

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Ankylosing Spondylitis is a disease characterized by abnormal bone structures (syndesmophytes) growing at intervertebral disk spaces. Because this growth is so slow as to be undetectable on plain radiographs taken over years, it is desirable to resort to computerized techniques to complement qualitative human judgment with precise quantitative measures. We(More)
PURPOSE To investigate a tetrahedral diffusion gradient encoding scheme to measure the diffusion tensor in vivo for human calf muscle. MATERIALS AND METHODS The theoretical TE which maximizes the signal-to-noise ratio (SNR) of the diffusion images was derived for both the orthogonal and tetrahedral sampling strategies and the SNR advantage verified(More)
Data analysis is an important part of the scientific process carried out by domain experts in data-intensive science. Despite the availability of several software tools and systems, their use in combination with each other for conducting complex types of analyses is a very difficult task for non-IT experts. The main contribution of this paper is to(More)
Laser forming has not been widely used due to limited understanding of its mechanism and immaturity of processing technology. In the study of single axis laser bending of plates, edge effects affect accuracy of the bending. Experimental and numerical studies are carried out to study the mechanism of the edge effects. Temperature dependency of material(More)
OBJECTIVE Scanning time considerations have restricted routine use of 3D Fourier transform (3DFT)-encoded MRI to gradient-recalled echo sequences. We sought to combine isotropic 3DFT acquisition with fast spin-echo at a practical scan duration. This strategy offers versatile image contrast for musculoskeletal evaluation and facilitates image reformation(More)
Ankylosing spondylitis is a disease characterized by abnormal bone formation (syndesmophyte) at the margins of inter-vertebral disc spaces. Syndesmophyte growth is currently typically monitored by the visual inspection of radiographs. The limitations inherent to the modality (2D projection of a 3D object) and rater (qualitative human judgment) may(More)