Lawrence Wolfgang

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Hyperinsulinemia increases sympathetic nerve activity and contributes to cardiovascular dysfunction in obesity and diabetes. Neurons of the hypothalamic paraventricular nucleus (PVN) regulate sympathetic nerve activity through mono- and poly-synaptic connections to preganglionic neurons in the spinal cord. The purpose of the present study was to determine(More)
Accumulating evidence suggests that insulin acts within the hypothalamus to alter sympathetic nerve activity (SNA) and baroreflex function. Although insulin receptors are widely expressed across the hypothalamus, recent evidence suggests that neurons of the arcuate nucleus (ARC) play an important role in the sympathoexcitatory response to insulin. The(More)
  • Clara Strohm, L Wolfgang, Uck Zweitgutachter, Michael Pd, Joachim, Ratcliffe Benedetti +2 others
  • 2004
Introduction Manifolds, the basic objects of geometry, form the playground for both to-pological and smooth structures. Many challenges in modern mathematics are concerned with the nature of this interaction between algebraic topology, differential topology and differential geometry. For example all incarnations of the index theorem, the Gauß-Bonnet(More)
Insulin acts within the central nervous system to regulate food intake and sympathetic nerve activity (SNA). Strong evidence indicates that glucocorticoids impair insulin-mediated glucose uptake and food intake. However, few data are available regarding whether glucocorticoids also modulate the sympathoexcitatory response to insulin. Therefore, the present(More)
  • Clara L Oh 2007 Mathematik, Clara Löh, Geb Strohm, Dekan Prof, Joachim H C Cuntz, Erster Gutachter +5 others
  • 2007
Introduction A pervasive theme of contemporary mathematics is to explore rigidity phenomena caused by the symbiosis of algebraic topology and Riemannian geometry on manifolds. In this context, the term " rigidity " refers to the astounding fact that certain topological invariants provide obstructions for geometric structures. Consequently , topological(More)
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