Lawrence Schultz

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Regioregular polythiophene-based conductive copolymers with highly crystalline nanostructures are shown to hold considerable promise as the active layer in volatile organic compound (VOC) chemresistor sensors. While the regioregular polythiophene polymer chain provides a charge conduction path, its chemical sensing selectivity and sensitivity can be altered(More)
The present study was undertaken to determine whether a cAMP pathway mediates the mobility of CD3, CD4, and CD8 within the membrane. Crosslinking CD3, CD4, and CD8 with monoclonal antibody and anti-antibody induced rapid accumulation of intracellular cAMP, occupancy of cAMP receptors, and was temporally associated with the mobilization and directed movement(More)
Bo Li a, Suresh Santhanam a, Lawrence Schultz b, Malika Jeffries-EL c, Mihaela C. Iovu c, Genevieve Sauvé c, Jessica Cooper c, Rui Zhang c, Joseph C. Revelli d, Aaron G. Kusne a, Jay L. Snyder d, Tomasz Kowalewski c, Lee E. Weiss b, Richard D. McCullough c, Gary K. Fedder a, David N. Lambeth a,∗ a Department of Electrical and Computer Engineering, Carnegie(More)
The present study was undertaken to establish whether cAMP-dependent phosphorylation of endogenous substrates is impaired in T lymphocytes from subjects with active systemic lupus erythematosus (SLE). In normal human T lymphocytes, the cell-permeable cAMP analog, N6,O2'-dibutyryladenosine 3',5'-cyclic monophosphate, induced phosphorylation of substrates(More)
Arachidonic acid (20:4) conversion to prostanoids was examined in murine peritoneal macrophages infected in vitro with Leishmania donovani. Four strains of mice differing in resistance to in vivo L. donovani infection were studied. Normal macrophages from all strains converted 20:4 to prostanoids and this was augmented by L. donovani infection. Although(More)
To determine whether a defect in the T cell response to adenosine exists at the level of the adenosine receptor in systemic lupus erythematosus (SLE) we measured the binding affinity and maximum binding of T cell membranes from both normal and SLE T cells by utilizing radiolabeled adenosine ligands. Normal T lymphocyte membranes possess a single class of(More)
The use of gold nanoparticles coated with an organic monolayer of thiol for application in chemiresistive sensors was initiated in the late 1990s; since then, such types of sensors have been widely pursued due to their high sensitivities and reversible responses to volatile organic compounds (VOCs). However, a major issue for chemical sensors based on(More)
New synthesis methods have allowed us to make many semiconducting polythiophenes polymers with different side and end groups. Also, co-polymers combining a polythiophene chain attached to another polymer chain were synthesized. This design freedom brings a new dimensionality to the sensing properties of the materials. Single chip micro sensor resistor(More)
The solid state reactions and structural evolution in nanocrystalline FePt powders during mechanical ball milling at 77 K and subsequent annealing have been investigated. Above 310 °C the formation of L10 FePt is observed. As the milling time increases, the enthalpy evolved during the transformations is reduced, whereas the corresponding activation energy(More)
In polycrystalline samples of superconducting MgCNi3, the critical temperature and the specific heat were measured as a function of magnetic field. A Wertheimer–Helfand–Hohenberg (WHH)-like shape of Hc2ðT Þ is observed. The Hc2ðT Þ and specific heat data are discussed on a qualitative level in terms of effective singleand multi-band models based on an(More)