Lawrence Rothenberg

Learn More
BACKGROUND The credibility of modern science is grounded on the perception of the objectivity of its scientists, but that credibility can be undermined by financial conflicts of interest. The US Public Health Service and the National Science Foundation issued regulations effective October 1, 1995, regarding the disclosure of financial interests in the(More)
Journal policies and requirements of funding agencies on financial disclosure of authors and grant applicants have divided editors and scientists who disagree on whether such policies can improve the integrity of science or manage conflicts of interest. Those opposed to such disclosure policies argue that financial interest is one of many interests held by(More)
Although political methodologists are well aware of measurement issues and the problems that can be created, such concerns are not always front and center when we are doing substantive research. Here, we show how choices in measuring legislative preferences have influenced our understanding of what determines legislative outputs. Specifically, we repli-cate(More)
I study the evolution of Statement of Financial Accounting Standard (SFAS) # 142, which uses unverifiable fair-value estimates to account for acquired goodwill. I find evidence consistent with the Financial Accounting Standards Board (FASB) issuing SFAS 142 in response to political pressure over its proposal to abolish pooling accounting: pro-pooling firms(More)
Purpose: This phase I study assessed the maximum tolerated dose (MTD), safety, tolerability, pharma-cokinetics (PK), and pharmacodynamics (PD) of SJG-136, a sequence-specific DNA cross-linking agent, in patients with advanced cancer. Experimental Design: In schedule A, seven patients received escalating doses of SJG-136 (6, 12, 24, and 48 mg/m 2) daily for(More)
  • 1