Lawrence R. Solomon

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Disorders of cobalamin (vitamin B12) metabolism: emerging concepts in pathophysiology, diagnosis and treatment.

Lawrence R. Solomon
Blood reviews
2007

Although cobalamin (vitamin B12) was isolated almost 60 years ago, its biochemical, physiologic and neurologic effects remain incompletely defined. New observations suggest renal regulation of… (More)

Cobalamin-responsive disorders in the ambulatory care setting: unreliability of cobalamin, methylmalonic acid, and homocysteine testing.

Early recognition of cobalamin (Cbl)-responsive disorders in the ambulatory care setting is essential to prevent irreversible neurologic deficits. However, diagnostic algorithms using Cbl,… (More)

Treatment and prevention of pain due to vaso-occlusive crises in adults with sickle cell disease: an educational void

Pain due to vaso-occlusive crisis is the major cause of hospital use in sickle cell disease. Although available guidelines provide recommendations for opioid administration in this setting, only 4… (More)

Pain management in adults with sickle cell disease in a medical center emergency department.

Lawrence R. Solomon
Journal of the National Medical Association
2010

Guidelines for pain management in adult sickle cell patients with vaso-occlusive crises suggest prompt, frequent administration of parenteral opioids. Neither the ability to implement these… (More)

Unique preS sequence in a gibbon-derived hepatitis B virus variant.

Larry T Mimms, Lawrence R. Solomon, J. W. Ebert, Hubert Fields
Biochemical and biophysical research…
1993

A unique hepatitis B virus (HBV) variant has been identified in a gibbon (Hylobates lar) which could be passed to a chimpanzee by experimental inoculation. This HBV variant had been shown to have no… (More)

Effect of pyridoxine (vitamin B6) on diabetic patients with peripheral neuropathy.

Kenneth Cohen, George Gorecki, Shira Silverstein, John S. Ebersole, Lawrence R. Solomon
Journal of the American Podiatry Association
1984

Morphologic, biochemical, and cytogenetic studies of bone marrow and circulating blood cells in painters exposed to ethylene glycol ethers.

Mark R Cullen, Lawrence R. Solomon, +5 authors Carrie A. Redlich
Environmental research
1992

In a previous cross-sectional survey, up to 15% of shipyard painters were found to have mild anemia or granulocytopenia, mostly acquired since employment. Environmental studies had suggested a… (More)

Ureaplasma urealyticum CAPD peritonitis following insertion of an intrauterine device: diagnosis by eubacterial polymerase chain reaction.

Elizabeth A Bailey, Lawrence R. Solomon, +6 authors Dave Pitcher
Peritoneal dialysis international : journal of…
2002

Diabetes as a Cause of Clinically Significant Functional Cobalamin Deficiency

Lawrence R. Solomon
Diabetes care
2011

OBJECTIVE Functional cobalamin (Cbl) deficiency (i.e., high methylmalonic acid [MMA] values despite normal serum Cbl levels) is common in the elderly and associated with neuropathy and anemia.… (More)

Erythrocyte O2 transport and metabolism and effects of vitamin B6 therapy in type II diabetes mellitus.

The effects of vitamin B6 on erythrocyte metabolism, erythrocyte hemoglobin O2 affinity (P50), and nonenzymatic glycosylation were studied in 15 Caucasian men with type II (non-insulin-dependent)… (More)

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