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Previous research suggests a close similarity in brain activity between mental simulation of a movement and its real counterpart. To explore this similarity, we aimed to assess whether imagery is affected by the loss of a limb or of its motor skills. We examined the performance of 16 adult, upper limb amputees (and age-matched controls) in a left/right hand(More)
Parkinson's disease is a common incurable neurodegenerative disease whose molecular aetiology remains unclear. The identification of Mendelian genes causing rare familial forms of Parkinson's disease has revealed novel proteins and pathways that are likely to be relevant in the pathogenesis of sporadic Parkinson's disease. Recently, mutations in a novel(More)
An exploration into cerebellar activity during the perception and production of speech and song may elucidate general underlying cerebellar functions. Recently, the cerebellum has been hypothesized to be involved with sharpening sensory input, temporal coordination and processing of motor articulation and perception, as well as instantiation of internal(More)
Ethnic differences in birthweight, perinatal mortality and other obstetric outcomes are now well known. In some districts with a significant ethnic minority population, services are provided for non-English-speaking women using maternity units. Various models have developed, including translators, interpreters, Linkworkers, the Department of Health funded(More)
A randomised cross-over trial was conducted to see if wet suits increase swimming speed--a question which has been fiercely debated in the fat-growing endurance sport of Triathlon. Sixteen swimmers volunteered to undertake two 30 minute swims, one with and one without a wet suit. With wet suits the subjects swam an average of 24.9 lengths of a 66 m pool.(More)
OBJECTIVE To examine the influence that being female has on the outcome of acute myocardial infarction. DESIGN Observational follow up study. SETTING London district general hospital. PATIENTS 216 women and 607 men with acute myocardial infarction admitted to a coronary care unit from 1 January 1988 to 31 December 1992. MAIN OUTCOME MEASURES All(More)