Lawrence Hale

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Preliminary studies with restriction fragment length polymorphisms of mitochondrial DNA (mtDNA) in natural populations of Drosophila melanogaster revealed considerable variation in terms of nucleotide sequence and overall size. In this report we present data from more isofemale lines and more restriction enzymes, and explore the utility of the data in(More)
Size variation and heteroplasmy in mitochondrial DNA (mtDNA) are relatively common in natural populations of Drosophila melanogaster. Of 92 isofemale lines of flies obtained from various geographic regions throughout the world, 75 lines were homoplasmic and showed a total of 12 different mtDNA size classes. The remaining 17 lines were heteroplasmic, each(More)
The understanding of the genetic structure of a species can be improved by considering together data from different types of genetic markers. In the past, a number of worldwide populations of Drosophila melanogaster have been extensively studied for several such markers, including allozymes, chromosomal inversions, and quantitative characters. Here we(More)
Verticillium wilt is an economically important disease that causes reduced tuber yields in potato. Pathogen population dynamics were studied during disease development following combined inoculations of potato withV. albo-atrum and various otherVerticillium species. In greenhouse and field studies, threeVerticillium species were examined:V. albo-atrum(More)
Drosophila melanogaster and its sibling speciesD. simulans have a cosmopolitan distribution. Studies on nuclear gene-enzyme variation from natural populations of these species reveal that the two have almost equal overall heterozygosity, yetD. simulans populations are significantly less differentiated. However, it is not clear whether this difference in(More)
Verticillium dahliae is a strong soil-borne pathogen that causes early dying of potato plants. Pathogen population dynamics were studied during disease development following combined inoculations of potato withV. dahliae and various otherVerticillium species. In greenhouse and field studies, threeVerticillium species were examined:V dahliae, V. albo-atrum(More)
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