Lawrence G Hutchins

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OBJECTIVE Computed tomography (CT) remains the first-line imaging procedure for pre-therapeutic staging of head and neck tumors. Non-Hodgkin lymphoma (NHL) is not easily distinguished from squamous cell carcinoma (SCC), especially because NHL often appears in extranodal locations. We sought to explore whether specific CT characteristics could be used to(More)
The magnetic resonance (MR) imaging studies and clinical records of 29 patients with typical or atypical trigeminal neuralgia (TN) were retrospectively reviewed and compared with the MR studies of 30 patients imaged for reasons unrelated to the fifth cranial nerve. The symptomatic patients were in three groups. Group 1 included those without masses or(More)
The clinical and radiologic records of 76 patients with trigeminal neuropathy and an abnormal imaging study (CT and/or MR) were analyzed retrospectively. The trigeminal nerve (cranial nerve V) was divided into proximal (brainstem, preganglionic, gasserian ganglion, and cavernous sinus) and distal (extracranial V1, V2, and V3) segments. Lesions were(More)
Alpha1-acid glycoprotein (alpha1-AG) was purified from human sera, and its binding properties with respect to psychotropic drugs were examined by equilibrium dialysis methods in order to clarify the specificity of binding. Radioactive imipramine, a tricyclic antidepressant, was used as the primary ligand. Other drugs, representative of different classes,(More)
Central nervous system metastases from diffuse malignant pleural mesothelioma are rare. Here we describe a patient without known asbestos exposure who presented with chest pain, increasing shortness of breath and persistent headache. Evaluation found biphasic malignant mesothelioma of the right hemithorax and a single brain metastasis confirmed by computed(More)
OBJECTIVE We sought to determine whether an advantage is obtained in the routine use of computed tomography (CT) scans in preoperative assessments of parotid tumors. METHODS A prospective study of 32 consecutive cases of patients who underwent evaluation for parotidectomies was performed. Twenty-nine received preoperative CT scans. The scans were(More)
18F-Labeled fluorotrimethylsilane was prepared by nucleophilic substitution of chlorotrimethylsilane with reactor produced [18F]fluoride. Hydrolysis of fluorotrimethylsilane by aqueous tetraethylammonium hydroxide followed by removal of water with a mechanical pump gave a powerful source of no carrier added nucleophilic 18F. Reaction of this purified 18F(More)
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