Lawrence Friedman

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All talking therapies profit from a patient's deliberate work in treatment, for a number of reasons, each of which deserves separate study and reflection. This is as true for psychoanalysis as for other psychotherapies. But in psychoanalysis the idea of a patient's deliberate work is paradoxical and problematic, bringing special overt and covert benefits,(More)
June 2006 | Volume 3 | Issue 6 | e144 Concerns about adverse events, including deaths, in recent large clinical trials, both publicly and privately sponsored, prompted Elias A. Zerhouni, Director, National Institutes of Health (NIH) to convene a meeting at the NIH on January 11–12, 2005, to discuss “Moving from Observational Studies to Clinical Trials: Why(More)
The mission of the National Heart, Lung, and Blood Institute is to sponsor research in the prevention, diagnosis, and treatment of heart, lung, and blood diseases. As a part of its activities toward this end, the Institute plans and conducts clinical trials that test the safety and efficacy of a broad range of preventive and treatment regimens. Many of(More)
1 Division of AIDS, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, United States of America, 2 ClinicalTrials.gov, National Library of Medicine, National Institutes of Health, Bethesda, Maryland, United States of America, 3 Department of Clinical Bioethics, Warren G. Magnusen Clinical Center,(More)
The NHLBI has recently developed standards for protection of subject confidentiality which enable distribution of large data sets collected in completed epidemiological studies and clinical trials. This allows other investigators to pursue research using the data these studies have generated. An ethical commitment to protect the privacy of the research(More)
The close-out of clinical trials that end ahead of schedule often involves problems that differ from those of trials that end as planned. The Beta-Blocker Heart Attack Trial (BHAT), a double-blind study of 3837 post-myocardial infarction patients, was a multicenter clinical trial that ended early because therapeutic benefit had been demonstrated. The(More)
One might say that the analyst counts on the patient's unconscious work, while conscious work is, to some extent, just one more thing to be deconstructed (analyzed). Analyst and patient, however, cannot avoid thinking that they are working on a common project, partly because the image of a mutual work distracts from the painfully uncertain illusion that the(More)
To avoid certain errors in practice, Charles Brenner offered an holistic substitute for the Freudian structural model of the mind. He used the term compromise formation ambiguously to refer to both actions and states, so as to render unnecessary what he considered artificial, judgmental attitudes embodied in images of psychic structures. He believed that a(More)