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In a prospective study of 505 hearing impaired and deaf students conducted at Children's Hospital Eye Clinic, 48.7% were found to have significant ocular abnormalities. The prevalence of myopia, astigmatism, and pathological intraocular changes was found to be significantly increased over the general population. In addition, the prevalence of ocular(More)
Utilizing a high intensity photographic flash unit, electroretinograms were recorded from normal adults under fully light adapted conditions over a 5 log unit range of stimulus luminance (-1.35 to 3.34 log cd-s/m2). At lower luminance levels b-wave amplitude increased with increased luminance until it reached a maximum (Vmax of the Naka-Ruston equation) in(More)
The negative afterimage from grating can be considered equivalent to a renal grating, the contrast of which decreases over time. The interval between the onset of the afterimage and the time at which the effective contrast of the afterimage falls below threshold defines afterimage duration. In a series of experiments with several predictions based on this(More)
Normative dark-adapted electroretinograms were recorded simultaneously with a skin electrode and corneal electrode for varying stimulus intensities. The electroretinogram b-wave amplitudes for each electrode were fitted by the Naka-Rushton equation, and the parameters Vmax, K and n were evaluated. A comparison of parameters between the two electrodes showed(More)
The Vistech Contrast Sensitivity Function tester (VCTS 6500-1) for distance was evaluated to determine the minimum age of children who could complete the test and to determine changes in the CSF as a function of age. A total of 72 normal children between the ages of 24 and 84 months were tested twice with each eye. The results revealed that no child below(More)
PURPOSE This study investigates interocular differences in the level and extent of cortical activation in amblyopic and normal subjects. SUBJECTS AND METHODS Blood oxygenation level dependent functional magnetic resonance imaging (FMRI) was performed at 1.5 T. A total of 5 subjects with amblyopia and 6 control subjectswere recruited. Visual stimuli(More)
To determine the tolerability and efficacy of levodopa/carbidopa combined with occlusion therapy for childhood amblyopia, a double-masked placebo-controlled randomized longitudinal study was performed on 10 amblyopic children between 6 and 14 years of age. Subjects received, on average, 20/5 mg levodopa/carbidopa or 20 mg of placebo three times per day(More)
PURPOSE We investigated the effects of a single dose of levodopa (L-dopa) on the level and extent of visual cortex activation of subjects with amblyopia and normal subjects using blood oxygenation level-dependent functional magnetic resonance imaging (fMRI). SUBJECTS AND METHODS Six patients with amblyopia and 9 control patients were recruited. A baseline(More)
PURPOSE To evaluate the efficacy and tolerance of two low doses of levodopa/carbidopa (25/6.25 mg, 50/12.5 mg) and placebo (Tums) in 20 children with amblyopia between the ages of 4 and 14 years. METHODS A double-masked placebo-controlled randomized 8-hour study was performed during which subjects received one of two doses of levodopa/carbidopa or(More)
Pattern visual-evoked response binocular summation (VERBS) was recorded in normal infants, between the ages of 1-58 months, and in similar-aged esotropic infants before and at various times after corrective surgery. The normal subjects had no significant VERBS at 1.5 months of age, developed a rapid acceleration of VERBS between 1.5-3 months, and then(More)