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AIM To test the hypothesis that glycaemic control with exenatide added to thiazolidinediones (TZDs) with or without metformin was superior to placebo. METHODS A 26-week, multi-country (Canada, Mexico, Romania, South Africa and the USA), randomized, double-blind, placebo-controlled study compared exenatide twice-daily vs. placebo in 165 subjects(More)
BACKGROUND Weight loss (WL) negatively affects bone mineral density (BMD) in older populations and has specifically been shown in women. OBJECTIVE In this prospective controlled trial, we examined variables of bone quality and endocrine changes after intentional WL in men. DESIGN Thirty-eight overweight and obese [mean ± SD body mass index (in kg/m²):(More)
OBJECTIVE To examine the relationship between endogenous serum estradiol and vitamin D-binding protein (DBP) and total, free, and bioavailable 25-hydroxyvitamin D (25OHD) concentrations in pre- and postmenopausal women. METHODS In 165 healthy women (ages, 26 to 75 years) not taking any form of exogenous estrogen, the serum concentrations of estradiol,(More)
UNLABELLED The epidemiological characteristics, the methods used in treating the patients, as well as the evolution of the myocardial infarction are not known in the Romanian county and municipal hospitals. MATERIAL AND METHODS Six hundred and fifty one cases of acute myocardial infarction were retrospectively recorded in the Emergency County Hospital of(More)
The effects of higher than recommended vitamin D doses on bone mineral density (BMD) and quality are not known. In this study, higher intakes, in postmenopausal women undergoing weight control over 1 year, had no effect on areal or volumetric BMD but prevented the deterioration in cortical bone geometry. Studies examining how bone responds to a standard(More)
The objective was to compare short-term mortality after a first acute myocardial infarction with ST elevation (STEMI) in patients with and without diabetes mellitus (DM). Between 1.01.2000 31.12.2009, 1335 STEMI patients were admitted in the Baia Mare Emergency Hospital: 660 (142 DM) had no thrombolysis, 675 (136 DM) received thrombolysis. In-hospital(More)
Accumulating evidence supports a complex relationship between adiposity and osteoporosis in overweight/obese individuals, with local interactions and endocrine regulation by adipose tissue on bone metabolism and fracture risk in elderly populations. This review was conducted to summarize existing evidence to test the hypothesis that obesity is a risk factor(More)
In Ophthalmological Clinic of the District Bucharest Hospital, the authors studied 59 patients with herpetic keratitis, and keratouveitis treated with Zovirax (acyclovir). They try to prove with clinical arguments the efficacity of this treatment in different forms of herpetic keratitis. The authors consider the acyclovir like the election therapy of ocular(More)
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