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JNPL3 transgenic mice expressing a mutant tau protein, which develop neurofibrillary tangles and progressive motor disturbance, were crossed with Tg2576 transgenic mice expressing mutant beta-amyloid precursor protein (APP), thus modulating the APP-Abeta (beta-amyloid peptide) environment. The resulting double mutant (tau/APP) progeny and the Tg2576(More)
We present measurements of a long-range smoke transport event recorded on 20–21 July 2011 over Hali-fax, Nova Scotia, Canada, during the Quantifying the impact of BOReal forest fires on Tropospheric oxidants over the Atlantic using Aircraft and Satellites (BORTAS-B) campaign. Ground-based Fourier transform spectrometers and photometers detected air masses(More)
Simulation of the land subdivision process is useful in many applied and research areas. Planners use such tools to understand potential impacts of planning regulations prior to their implementation. While the credibility of both land-use change and urban growth models would be enhanced by integrating capabilities to simulate land subdivision, such research(More)
There is an urgent need within the international remote sensing community to establish a metadata standard for field spectroscopy that ensures high quality, interoperable metadata sets that can be archived and shared efficiently within Earth observation data sharing systems. Careful examination of all stages of metadata collection and analysis can inform a(More)
(2009), The genome and structural proteome of an ocean siphovirus: a new window into the cyanobacterial 'mobilome'. The MIT Faculty has made this article openly available. Please share how this access benefits you. Your story matters. ABSTRACT: Prochlorococcus, an abundant phototroph in the oceans, are infected by members of three families of viruses:(More)
Field and laboratory spectroscopy is a common method applied by different remote sensing user communities for various purposes, ranging from calibration/validation experiments to material identification (Milton 2009; Haest, et al. 2013). In all cases a large number of spectra tend to be collected, yet the value and sharing of such collections is often(More)
Scientific efforts to observe the state of natural systems over time, allowing the prediction of future states, have led to a burgeoning interest for organised storage of spectral field data and associated metadata, seen as being key to the successful and efficient modeling of such systems. A centralised system for such data established for the Australian(More)
The establishment of invasive weeds in wetland environments is a prominent threat in Australia with adverse impacts on native flora. Current management is hindered by the lack of information available on which to base and justify management interventions, in particular, mapping of weed distributions. Remote sensing is a possible solution to difficulties of(More)
  • David Secko, Vancouver References, Jc Dodart, Marr Ra, Koistinaho M, Gregersen Bm +15 others
  • 2005
T he risk of Alzheimer's disease may come down to the expression of various forms of the human apolipoprotein E gene (apoE). Jean-Cosme Dodart and colleagues 1 have recently shown that injecting a variant of apoE into the brains of mice has an effect on the formation of the amyloid plaques characteristic of Alzheimer's disease. Their research contributes(More)