Lauri Siivonen

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To assess the suggested etiological role of human papillomavirus (HPV), biopsies from 14 patients operated on for an inverted papilloma (11 cases) and squamous cell carcinoma (3 cases) of the nasal cavity and paranasal sinuses were analysed for light microscopical evidence of HPV, by indirect immunoperoxidase (IP-PAP) to demonstrate HPV structural proteins,(More)
In order to increase the flexibility and performance of hydraulically actuated machines there is a demand for more intelligent controllers. This leads to a rapid increase in complexity of the control systems. To manage the complexity and to ensure reliability of these systems, adequate software development methods are needed. In this work, we propose a(More)
Sex steroid hormone receptors (SSHR) were determined in 14 cases of sinonasal papillomas, 17 cases of nasal polyps and in the normal nasal mucosa of 13 patients. The determination of SSHR was done by the dextran-coated charcoal assay from cytosol protein. All the cases of sinonasal papilloma were SSHR negative, while some specimens of normal nasal mucosa(More)
Transitional papilloma is a rare but not uncommon tumor with an overall incidence varying between 0.5 and 4% of all primary nasal tumors. The probability of recurrence is high, between 20 and 62%, even after adequate therapy. Malignancies are associated with transitional papilloma in 2-13% of cases. A series of 21 patients with transitional papilloma of the(More)
The nuclear DNA content of 19 transitional papillomas of the sinonasal region and 9 maxillary squamous cell carcinomas was studied by flow cytometry; the presence of human papillomavirus (HPV) DNA types 11 and 16 was determined by the in situ hybridization technique from paraffin-embedded tissue. Thirteen (68%) of the papillomas and none of the carcinomas(More)
The efficacy and side effects of once-daily astemizole-D, a combination of 10 mg astemizole and 240 mg pseudoephedrine, were compared with those of twice-daily brompheniramine-D, a combination of 12 mg brompheniramine and 50 mg phenylpropanolamine (Lunerin), in 64 patients with seasonal allergic rhinitis caused by birch pollen. Efficacy was monitored by(More)
Untersuchungen des Instituts für Wildforschung ergaben, daß die Bestandesschwankungen bei allen Tetraonen in Nordwesteuropa seit der Jahrhundertwende in drei bis vierjährigem Rhythmus stattfanden. Die Depression des Rückganges zeigte sich schon im Vorjahr durch Rückgang der Legefreudigkeit an. Die Bestandsschwankungen der Tetraonen sind identisch mit den(More)
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